Introduction: Quinolone carboxylic antibacterial agent is considerably lethal against gram-negative bacteria, especially Chlamydia trachomatis that have complicated intracellular structure. On the other hand, Anti C. trachomatis infection agent should be having specific proprieties such as being able to penetrate eukaryotic cells in bacteria
Method:
The efficiency of quinolones can show in vitro by two ways. Firstly, the infected cell may be exposed to different types of quinolone antibacterial. Secondly, McCoy cell monolayers should inoculate with 103 (IFU) OF C. trachomatis then incubate with or without ofloxacin.
Result:
The main results of testing anti-bacterial agents will show in this paragraph. The effects of four types of antibacterial (Ofloxacin, Ciprofloxacin, Enoxacin and Norfloxacin) in McCoy cell are different. The results may refer to the different abilities for each antibacterial to penetrate the eukaryotic cell. Moreover, the infected cell may not increase the time of incubation after the removal of anti-bacterial agents creating a little different between MIC and MLC for each antibacterial agent.
On the other hand, Ofloxacin antibacterial agent may act contrary to some enzymes that are important for the survival of non-replicating intracellular chlamydia. As such, Ofloxacin has a responsibility of treating determined and calm infection.
Conclusion:
This study derives and presents four important points. Firstly, quinolone antibacterial agent acts quickly against chlamydia. Secondly, Ofloxacin considers suitable antimicrobial agent against chlamydia infection. Thirdly, humans can achieve and maintain 1mg/l of Ofloxacin in serum. Therefore, the clinical experiment against chlamydia infection will be of interest. Finally, Ofloxacin may give us a tool to show the importance of DNA metabolism in non-replicating intracellular chlamydia organized by topoisomerases.
Related Essay Samples
Article matrix
Journal of Arts, Science & Commerce To explore the existing relationship between the styles of leadership and the managers' motivation in the organizations The study is in the form of a review of written literature on the issue on leadership ...
Book review: what matters? putting common sense to work
More on that question mark in the title later, but the words presage a concern with what matters to us as cognitive agents as we engage purposefully with our world and what we, as cognitive scientists and designers of cognitive ...
Editorial: health-related complications of acromegaly
Cancer incidence in patients with acromegaly: a cohort study and meta-analysis of the literature. 14: 3484 9.doi: 10.
Mycn function in neuroblastoma development
Lower Panel: While C-Myc is the main regulator in pluripotent cells of early embryonal development, MycN is highly expressed in the multipotent cells of the migratory and post-migratory neural crest. During differentiation, MycN expression is downregulated and the sympathoadrenal precursor ...
Sample research paper on the career of a chiropractor
A chiropractor would do anything to reduce the pain a patient is going through with the sole aim of improving the functionality of the patient while at the same time educating these patients on how to go about improving their ...
lactobacillus helveticus : importance in food and health
These genes and their derived enzymes underline the well known propensity of L.helveticus to be used as dairy starter in the production of cheese and cheese derivatives. To this regard, the review of Griffiths and Tellez described more specifically the ...
The importance of we in power: integrating police wellness and ethics
Police officers and the mental health experts who work with them need to be aware of the synergistic effect between police officers' ethical decision-making and their emotional health. The POWER perspective of wellness, ethics, and resilience helps law enforcement agencies ...
Understanding human–technology relations within technologization and appification of musicality
By bringing together the theoretical approaches of enactive cognition and Ihde's post-phenomenology, we aim at developing an understanding of the coevolution of technology and human musicality in relational terms and how the experience of technology and music is co-constituted in ...
Questions regarding the implementation of eu mutagenesis ruling in france
In reaction to the ruling of the European Court of Justice on mutagenesis, the French Conseil d'etat decided on a lawsuit brought in by various French farmer- and NGO-bodies concerning the national implementation of the mutagenesis exemption clause as ...
What are the grand challenges for plant conservation in the 21st century?
Data on distribution, changes in abundance and genetic diversity can inform the prioritization of conservation funding and effort, and research aimed at advancing conservation and management of plants and the processes that maintain healthy ecosystems. Both correlative and mechanistic approaches ...
Gestational diabetes: pathophysiology, etiology, signs and symptoms, interventions research paper examples
This activation then triggers a cascade of activation of various protein molecules leading to translocation of glucose transporter to the plasma membrane and influx of glucose. A 75 or 100 g solution of glucose is ingested by the pregnant patient ...
Essay on how quality of care issues relate to legal, ethical, and financial considerations
The total cost of medical is one of the quality issues in improving quality of care. Health care providers claim that their main motive for merger is to improve efficiency and the quality of care.
Reducing drug-induced deaths article review sample
Substance abuse leads to negative effects on both behavior and health of the users. Drug abuse is a problem to the individual, nation and community.
Is redox signaling a feasible target for overcoming multidrug resistance in cancer chemotherapy?
After that, cancer cells adapt to oxidative stress and counteract the potential toxic effects of ROS to promote cell proliferation, survival and metabolic adaptation to the tumor microenvironment: sustained cell proliferation and mitogenic signaling, increased cell survival and disruption of ...
Narrative reconsiderations of teaching as negotiated curriculum for social justice and equity
We root our work on issues of social justice and equity in curriculum and mentoring within particular experiences that enable us to shift between curriculum landscapes that centralize theories and those that explore students' and teachers' experiences of diversity. Connelly ...
Strategies for preparing a health care organization for change
The plan should indicate the goals and objectives of the change being instituted, roles of top management, and the period estimated for the entire process. Effective communication and training There should be concentrated effort to inform the staff of the ...
Early detection of perinatal asphyxia health and social care essay
Meconium aspiration syndrome is often associated with foetal hypoxia which promotes meconium discharge in amnionic fluid, panting and aspiration of MSAF, and besides alterations in the vascular muscular media of pneumonic arterias of the foetus. In France, the prevalence of ...
The grand challenges to air pollution
Current and future air pollution and ozone variability in the troposphere and stratosphere need to be addressed. The role of air pollution in asthma and other pediatric morbidities.J.
Inos associates with poor survival in melanoma: a role for nitric oxide in the pi3k-akt pathway stimulation and pten s-nitrosylation
Previous studies showed that the constitutive activation of the PI3K-AKT pathway occurred in the setting of PTEN loss of expression and function, which was detected in up to 30% of cutaneous melanomas. Supporting the clinical significance of activation of the ...
Love is governed by a brain
This does not support the argument that love is merely an addiction. On the other hand, any addiction is contrary to this intimacy involved in love.
Corrigendum: identification of cerebral metal ion imbalance in the brain of ageing octodon degus
00066 Due to a misunderstanding, the O.degus brain specimen used in the study were obtained from the animal facility of the Pontificia Universidad Catholic University of Chile, not the animal facility of the University of Valparaiso as previously stated in ...
Book review: innovations and challenges in language learning motivation
The first three chapters focus on the fundamental challenges, covering the following topics: the conceptualization of motivation, motivation dynamics, and motivation applied. In response to " non-L2-specificity challenge", the author proposes taking a " small lens approach" which means a ...
Stepping from modeling cancer plasticity to the philosophy of cancer
The immune system in this extended sense should thus comprise the following: the equivalent in all Metazoans of the major histocompatibility complex of jawed vertebrates, in charge of characterizing all cells of a given individual within its species; the immune ...
Drinking & congenital birth defects: alcohol awareness in the northern rivers region
8% acknowledging the use of alcohol during pregnancy, it is clear that there is low level of awareness in the public on the effects of alcohol consumption. However education can increase the awareness of the population on negative effects of ...
Emotion and anticipation in an enactive framework for cognition (response to andy clark)
Perhaps surprisingly, Clark acknowledges the existence of a " virtual version of the sensory data", but with no reference to some of the historical debates that shaped cognitive science, related to the storage, manipulation, and retrieval of representations in a ...